8ECR
KRAS4B 1-185 (C185S) bound to GDP-Mg2+
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | GTPase KRas | polymer | 185 | 21100.1 | 2 | UniProt (P01116) Pfam (PF00071) | Homo sapiens (human) | K-Ras 2,Ki-Ras,c-K-ras,c-Ki-ras |
| 2 | C, F (A, B) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) PubChem (888) | |||
| 3 | D, G (A, B) | GUANOSINE-5'-DIPHOSPHATE | non-polymer | 443.2 | 2 | Chemie (GDP) | |||
| 4 | E (A) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) PubChem (753) | |||
| 5 | H, I (A, B) | water | water | 18.0 | 327 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 185 (UniProt: P01116)
| PDB | External Database | Details |
|---|---|---|
| Ser 185 | Cys 185 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 42200.1 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 1027.1 | |
| All* | Total formula weight | 43227.2 |
