8EC5
Structures of HLA-B8E76C loaded with long peptides reveal novel features at the N-terminus of the groove
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | MHC class I antigen | polymer | 276 | 31902.0 | 1 | UniProt (R4ZGR5) Pfam (PF00129) Pfam (PF07654) UniProt (by SIFTS) (Q5SS57) | Homo sapiens (human) | |
| 2 | B (B) | Beta-2-microglobulin | polymer | 99 | 11748.2 | 1 | UniProt (P61769) Pfam (PF07654) | Homo sapiens (human) | |
| 3 | C (C) | peptide RARARARARARAFVKKKYCL | polymer | 20 | 2401.0 | 1 | Human immunodeficiency virus 1 | ||
| 4 | D, E, F (A, B, C) | water | water | 18.0 | 357 | Chemie (HOH) |
Sequence modifications
A: 1 - 276 (UniProt: R4ZGR5)
| PDB | External Database | Details |
|---|---|---|
| Cys 76 | Glu 100 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 46051.1 | |
| All* | Total formula weight | 46051.1 |
