8EA5
NKG2D complexed with inhibitor 1a
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | NKG2-D type II integral membrane protein | polymer | 129 | 14880.8 | 2 | UniProt (P26718) Pfam (PF00059) In PDB | Homo sapiens (human) | Killer cell lectin-like receptor subfamily K member 1,NK cell receptor D,NKG2-D-activating NK receptor |
| 2 | A | (3S,5aS,8aR)-3-benzyl-6-[(3,5-dichlorophenyl)methyl]-1,4-dimethyloctahydropyrrolo[3,2-e][1,4]diazepine-2,5-dione | non-polymer | 446.4 | 1 | Chemie (VN8) | |||
| 3 | A, B | TRIETHYLENE GLYCOL | non-polymer | 150.2 | 2 | Chemie (PGE) | |||
| 4 | water | water | 18.0 | 126 | Chemie (HOH) |
Sequence modifications
A, B: 90 - 216 (UniProt: P26718)
| PDB | External Database | Details |
|---|---|---|
| Met 88 | - | initiating methionine |
| Gly 89 | - | expression tag |
| Glu 117 | Ser 117 | engineered mutation |
| Ser 173 | Ile 173 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 29761.7 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 746.7 | |
| All* | Total formula weight | 30508.4 |
