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SummaryStructural detailsExperimental detailsFunctional detailsSequence NeighborHistoryDownloads

8EA0

CryoEM structure of miniGq-coupled hM3R in complex with iperoxo (local refinement)

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)		Muscarinic acetylcholine receptor M3polymer56862966.61UniProt (P20309)
Pfam (PF00001)		Homo sapiens (human)
2B
(A)		4-(4,5-dihydro-1,2-oxazol-3-yloxy)-N,N,N-trimethylbut-2-yn-1-aminiumnon-polymer197.31Chemie (IXO)
3C
(A)		CHOLESTEROL HEMISUCCINATEnon-polymer486.71Chemie (Y01)
Sequence modifications
A: 46 - 463 (UniProt: P20309)
A: 464 - 590 (UniProt: P20309)
PDBExternal DatabaseDetails
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Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight62966.6
Non-Polymers*Number of molecules2
Total formula weight684.0
All*Total formula weight63650.6
*Water molecules are not included.

246905

PDB entries from 2025-12-31

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