8E95

Mycobacterium tuberculosis RNAP elongation complex

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	DNA-directed RNA polymerase subunit alpha	polymer	347	37745.3	2	UniProt (A5U8D3) Pfam (PF01193) Pfam (PF01000) Pfam (PF03118) UniProt (by SIFTS) (P9WGZ1) In PDB	Mycobacterium tuberculosis	RNAP subunit alpha,RNA polymerase subunit alpha,Transcriptase subunit alpha
2	C	DNA-directed RNA polymerase subunit beta	polymer	1172	129372.0	1	UniProt (A5U052) Pfam (PF04563) Pfam (PF04561) Pfam (PF04565) Pfam (PF10385) Pfam (PF00562) Pfam (PF04560) UniProt (by SIFTS) (P9WGY9) In PDB	Mycobacterium tuberculosis	RNAP subunit beta,RNA polymerase subunit beta,Transcriptase subunit beta
3	D	DNA-directed RNA polymerase subunit beta'	polymer	1318	147097.1	1	UniProt (A0A045J9E2) Pfam (PF04997) Pfam (PF00623) Pfam (PF04983) Pfam (PF05000) Pfam (PF04998) UniProt (by SIFTS) (P9WGY7) In PDB	Mycobacterium tuberculosis	RNAP subunit beta',RNA polymerase subunit beta',Transcriptase subunit beta'
4	E	DNA-directed RNA polymerase subunit omega	polymer	110	11819.1	1	UniProt (A0A0T9N9K3) Pfam (PF01192) UniProt (by SIFTS) (P9WGY5) In PDB	Mycobacterium tuberculosis	RNAP omega subunit,RNA polymerase omega subunit,Transcriptase subunit omega
5	P	DNA (33-MER)	polymer	54	16521.6	1		synthetic construct
6	Q	DNA (25-MER)	polymer	54	16589.6	1		synthetic construct
7	R	RNA (5'-R(P*CP*GP*GP*AP*GP*AP*GP*GP*UP*A)-3')	polymer	20	6510.0	1		synthetic construct
8	D	ZINC ION	non-polymer		65.4	2	Chemie (ZN)
9	D	MAGNESIUM ION	non-polymer		24.3	1	Chemie (MG)

Sequence modifications

D: 1 - 1316 (UniProt: A0A045J9E2)

PDB	External Database	Details
Gly -1	-	expression tag
Ala 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	8
	Total formula weight	403400.0
Non-Polymers*	Number of molecules	3
	Total formula weight	155.1
All*	Total formula weight	403555.1

*Water molecules are not included.