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8E8B

Human DNA polymerase eta-DNA-rU-ended primer ternary mismatch complex:ground state at pH7.0 (K+ MES) with 1 Ca2+ ion

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
DNA polymerase etapolymer43548617.71UniProt (Q9Y253)
Pfam (PF00817)
Pfam (PF21704)
Pfam (PF11799)
Homo sapiens (human)RAD30 homolog A,Xeroderma pigmentosum variant type protein
2B
(T)
DNA (5'-D(*CP*AP*TP*TP*AP*TP*GP*AP*CP*GP*CP*T)-3')polymer123637.41synthetic construct
3C
(P)
DNA/RNA (5'-D(*AP*GP*CP*GP*TP*CP*A)-R(P*U)-3')polymer82428.61synthetic construct
4D
(A)
2'-DEOXYGUANOSINE-5'-TRIPHOSPHATEnon-polymer507.21Chemie (DGT)
5E
(A)
POTASSIUM IONnon-polymer39.11Chemie (K)
6F
(A)
CALCIUM IONnon-polymer40.11Chemie (CA)
7G, H, I
(A, T, P)
waterwater18.040Chemie (HOH)
Sequence modifications
A: 1 - 432 (UniProt: Q9Y253)
PDBExternal DatabaseDetails
Gly -2-expression tag
Pro -1-expression tag
His 0-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains3
Total formula weight54683.7
Non-Polymers*Number of molecules3
Total formula weight586.4
All*Total formula weight55270.0
*Water molecules are not included.

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PDB entries from 2024-10-30

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