8E82
Mycobacterium tuberculosis RNAP elongation complex with NusG transcription factor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | DNA-directed RNA polymerase subunit alpha | polymer | 347 | 37745.3 | 2 | UniProt (A5U8D3) Pfam (PF01193) Pfam (PF01000) Pfam (PF03118) UniProt (by SIFTS) (P9WGZ1) | Mycobacterium tuberculosis | RNAP subunit alpha,RNA polymerase subunit alpha,Transcriptase subunit alpha |
| 2 | C (C) | DNA-directed RNA polymerase subunit beta | polymer | 1172 | 129372.0 | 1 | UniProt (A5U052) Pfam (PF04563) Pfam (PF04561) Pfam (PF04565) Pfam (PF10385) Pfam (PF00562) Pfam (PF04560) UniProt (by SIFTS) (P9WGY9) | Mycobacterium tuberculosis | RNAP subunit beta,RNA polymerase subunit beta,Transcriptase subunit beta |
| 3 | D (D) | DNA-directed RNA polymerase subunit beta' | polymer | 1318 | 147097.1 | 1 | UniProt (A0A045J9E2) Pfam (PF04997) Pfam (PF00623) Pfam (PF04983) Pfam (PF05000) Pfam (PF04998) UniProt (by SIFTS) (P9WGY7) | Mycobacterium tuberculosis | RNAP subunit beta',RNA polymerase subunit beta',Transcriptase subunit beta' |
| 4 | E (E) | DNA-directed RNA polymerase subunit omega | polymer | 110 | 11819.1 | 1 | UniProt (A0A0T9N9K3) Pfam (PF01192) UniProt (by SIFTS) (P9WGY5) | Mycobacterium tuberculosis | RNAP omega subunit,RNA polymerase omega subunit,Transcriptase subunit omega |
| 5 | F (Z) | Transcription termination/antitermination protein NusG | polymer | 238 | 25439.4 | 1 | UniProt (A0A045HU92) Pfam (PF02357) UniProt (by SIFTS) (P9WIU9) | Mycobacterium tuberculosis | |
| 6 | G (P) | DNA (54-MER) | polymer | 54 | 16521.6 | 1 | synthetic construct | ||
| 7 | H (Q) | DNA (54-MER) | polymer | 54 | 16589.6 | 1 | synthetic construct | ||
| 8 | I (R) | RNA (5'-R(P*CP*GP*GP*AP*GP*AP*GP*GP*UP*A)-3') | polymer | 20 | 6510.0 | 1 | synthetic construct | ||
| 9 | J, K (D) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 10 | L (D) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) |
Sequence modifications
D: 1 - 1316 (UniProt: A0A045J9E2)
Z: 2 - 238 (UniProt: A0A045HU92)
| PDB | External Database | Details |
|---|---|---|
| Gly -1 | - | expression tag |
| Ala 0 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Val 1 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 9 |
| Total formula weight | 428839.4 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 155.1 | |
| All* | Total formula weight | 428994.5 |
