8E7T
Crystal structure of Middle East respiratory syndrome coronavirus (MERS-CoV) 3CL protease inactive mutant C148A
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | 3C-Like Protease | polymer | 306 | 33322.1 | 4 | UniProt (W6A941) Pfam (PF05409) UniProt (by SIFTS) (K9N7C7) | Middle East respiratory syndrome-related coronavirus (MERS-CoV) | |
| 2 | E, F, G, H, L... (A, B, C) | GLYCEROL | non-polymer | 92.1 | 9 | Chemie (GOL) | |||
| 3 | I, J, K, Q, R (B, C, D) | SODIUM ION | non-polymer | 23.0 | 5 | Chemie (NA) | |||
| 4 | S, T, U, V (A, B, C, D) | water | water | 18.0 | 553 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 1 - 306 (UniProt: W6A941)
| PDB | External Database | Details |
|---|---|---|
| Ala 148 | Cys 3395 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 133288.4 | |
| Non-Polymers* | Number of molecules | 14 |
| Total formula weight | 943.8 | |
| All* | Total formula weight | 134232.2 |
