8E7I
Cryo-EM structure of cardiac amyloid fibril from a variant ATTR P24S amyloidosis patient
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E | Transthyretin protein | polymer | 147 | 15894.9 | 5 | UniProt (P02766) Pfam (PF00576) In PDB | Homo sapiens (human) |
Sequence modifications
A, B, C, D, E: -19 - 127 (UniProt: P02766)
| PDB | External Database | Details |
|---|---|---|
| Ser 24 | Pro 44 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 5 |
| Total formula weight | 79474.7 | |
| All* | Total formula weight | 79474.7 |
