8E5N
Structure of ARG1 complex with pyrrolidine-based non-boronic acid inhibitor 10
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C, D, E... | Arginase-1 | polymer | 322 | 34779.9 | 6 | UniProt (P05089) Pfam (PF00491) In PDB | Homo sapiens (human) | Liver-type arginase,Type I arginase |
2 | A, B, C, D, E... | MANGANESE (II) ION | non-polymer | 54.9 | 12 | Chemie (MN) | |||
3 | A, B, C, D, E... | 1-{[(3S,4S)-3-(3-fluorophenyl)-4-{[4-(1,3,4-triethyl-1H-pyrazol-5-yl)piperidin-1-yl]methyl}pyrrolidin-1-yl]methyl}cyclopentane-1-carboxylic acid | non-polymer | 538.7 | 6 | Chemie (UL0) | |||
4 | water | water | 18.0 | 16 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 6 |
Total formula weight | 208679.3 | |
Non-Polymers* | Number of molecules | 18 |
Total formula weight | 3891.7 | |
All* | Total formula weight | 212571.0 |