8E5M
Structure of ARG1 complex with pyrrolidine-based non-boronic acid inhibitor 6
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C, D, E... | Arginase-1 | polymer | 322 | 34779.9 | 6 | UniProt (P05089) Pfam (PF00491) In PDB | Homo sapiens (human) | Liver-type arginase,Type I arginase |
2 | A, B, C, D, E... | MANGANESE (II) ION | non-polymer | 54.9 | 12 | Chemie (MN) | |||
3 | A, B, C, D, E... | 1-{[(3S,4S)-3-({4-[2-(4-fluorobenzene-1-sulfonyl)ethyl]piperidin-1-yl}methyl)-4-(3-fluorophenyl)pyrrolidin-1-yl]methyl}cyclopentane-1-carboxylic acid | non-polymer | 574.7 | 6 | Chemie (UKR) | |||
4 | water | water | 18.0 | 1126 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 6 |
Total formula weight | 208679.3 | |
Non-Polymers* | Number of molecules | 18 |
Total formula weight | 4107.6 | |
All* | Total formula weight | 212786.9 |