8E5M

Structure of ARG1 complex with pyrrolidine-based non-boronic acid inhibitor 6

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E... (A, B, C, D, E...)	Arginase-1	polymer	322	34779.9	6	UniProt (P05089) Pfam (PF00491)	Homo sapiens (human)	Liver-type arginase,Type I arginase
2	G, H, J, K, M... (A, B, C, D, E...)	MANGANESE (II) ION	non-polymer		54.9	12	Chemie (MN)
3	I, L, O, R, U... (A, B, C, D, E...)	1-{[(3S,4S)-3-({4-[2-(4-fluorobenzene-1-sulfonyl)ethyl]piperidin-1-yl}methyl)-4-(3-fluorophenyl)pyrrolidin-1-yl]methyl}cyclopentane-1-carboxylic acid	non-polymer		574.7	6	Chemie (UKR)
4	AA, BA, CA, DA, Y... (C, D, E, F, A...)	water	water		18.0	1126	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	208679.3
Non-Polymers*	Number of molecules	18
	Total formula weight	4107.6
All*	Total formula weight	212786.9

*Water molecules are not included.