8E1D
NMR-derived ensemble of the TAZ2 domain of p300 bound to the microphthalmia-associated transcription factor
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | B | Microphthalmia-associated transcription factor | polymer | 34 | 3720.1 | 1 | UniProt (O75030) In PDB | Homo sapiens (human) | Class E basic helix-loop-helix protein 32,bHLHe32 |
2 | A | Histone acetyltransferase p300 | polymer | 92 | 10107.9 | 1 | UniProt (Q09472) Pfam (PF02135) In PDB | Homo sapiens (human) | p300 HAT,E1A-associated protein p300,Histone butyryltransferase p300,Histone crotonyltransferase p300,Protein 2-hydroxyisobutyryltransferase p300,Protein lactyltransferas p300,Protein propionyltransferase p300 |
3 | A | ZINC ION | non-polymer | 65.4 | 3 | Chemie (ZN) |
Sequence modifications
B: 109 - 141 (UniProt: O75030)
A: 1723 - 1812 (UniProt: Q09472)
PDB | External Database | Details |
---|---|---|
Gly 108 | - | expression tag |
PDB | External Database | Details |
---|---|---|
Gly 1721 | - | expression tag |
Ser 1722 | - | expression tag |
Ala 1738 | Cys 1738 | engineered mutation |
Ala 1746 | Cys 1746 | engineered mutation |
Ala 1789 | Cys 1789 | engineered mutation |
Ala 1790 | Cys 1790 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 13828.0 | |
Non-Polymers* | Number of molecules | 3 |
Total formula weight | 196.2 | |
All* | Total formula weight | 14024.3 |