8E14

Cryo-EM structure of Rous sarcoma virus strand transfer complex

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E... (A, B, C, D, E...)	integrase	polymer	278	30926.6	8	UniProt (P03354) Pfam (PF02022) Pfam (PF00665) Pfam (PF00552)	Rous sarcoma virus - Prague C
2	I, L (I, L)	DNA (42-MER)	polymer	42	13047.5	2		Rous sarcoma virus - Prague C
3	J, M (J, M)	DNA (5'-D(*AP*AP*TP*GP*TP*TP*GP*TP*CP*TP*TP*AP*TP*GP*CP*AP*AP*TP*AP*CP*TP*C)-3')	polymer	22	6716.4	2		Rous sarcoma virus - Prague C
4	K, N (K, N)	DNA (5'-D(*AP*GP*TP*GP*TP*CP*TP*TP*CP*TP*TP*CP*TP*TP*TP*C)-3')	polymer	16	4821.1	2		Rous sarcoma virus - Prague C
5	O, P (A, E)	ZINC ION	non-polymer		65.4	2	Chemie (ZN)

Sequence modifications

A, B, C, D, E, F, G, H: 1 - 278 (UniProt: P03354)

PDB	External Database	Details
Lys 166	Arg 1446	variant

Contents of the asymmetric unit

Polymers	Number of chains	14
	Total formula weight	296582.5
Non-Polymers*	Number of molecules	2
	Total formula weight	130.8
All*	Total formula weight	296713.4

*Water molecules are not included.