8E00
Symmetry expansion of yeast cytoplasmic dynein-1 bound to Lis1 in the chi conformation.
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Dynein heavy chain, cytoplasmic | polymer | 2875 | 331524.0 | 1 | UniProt (A0A8H4FAJ6) Pfam (PF08393) Pfam (PF18198) Pfam (PF12774) Pfam (PF21499) Pfam (PF12775) Pfam (PF17857) Pfam (PF12780) Pfam (PF12777) Pfam (PF12781) Pfam (PF03028) UniProt (by SIFTS) (P36022) In PDB | Saccharomyces cerevisiae (baker's yeast) | Dynein heavy chain,cytosolic |
2 | B, C | Nuclear distribution protein PAC1 | polymer | 495 | 57030.6 | 2 | UniProt (P39946) Pfam (PF00400) In PDB | Saccharomyces cerevisiae (baker's yeast) | Lissencephaly-1 homolog,LIS-1,nudF homolog |
3 | A | ADENOSINE-5'-TRIPHOSPHATE | non-polymer | 507.2 | 3 | Chemie (ATP) | |||
4 | A | ADENOSINE-5'-DIPHOSPHATE | non-polymer | 427.2 | 1 | Chemie (ADP) |
Sequence modifications
A: 1218 - 4092 (UniProt: A0A8H4FAJ6)
B, C: 1 - 494 (UniProt: P39946)
PDB | External Database | Details |
---|---|---|
Gly 1218 | Asn 1218 | conflict |
Phe 1575 | Leu 1575 | conflict |
Ser 1578 | Phe 1578 | conflict |
Glu 1668 | Gln 1668 | conflict |
Val 1777 | Ile 1777 | conflict |
Val 1984 | Ile 1984 | conflict |
Gln 2488 | Glu 2488 | engineered mutation |
Val 2936 | Ile 2936 | conflict |
Gln 3266 | Arg 3266 | conflict |
Gly 3343 | Ala 3343 | conflict |
Val 3444 | Ile 3444 | conflict |
Arg 3556 | Lys 3556 | conflict |
Asp 3742 | Asn 3742 | conflict |
Val 3895 | Phe 3895 | conflict |
Asp 4072 | Asn 4072 | conflict |
PDB | External Database | Details |
---|---|---|
Gly 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 3 |
Total formula weight | 445585.2 | |
Non-Polymers* | Number of molecules | 4 |
Total formula weight | 1948.7 | |
All* | Total formula weight | 447534.0 |