8DZR
GR89,696 bound Kappa Opioid Receptor in complex with gustducin
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Kappa-type opioid receptor | polymer | 287 | 32289.4 | 1 | UniProt (P41145) Pfam (PF00001) | Homo sapiens (human) | K-OR-1,KOR-1 |
| 2 | B (B) | G alpha gustducin protein | polymer | 354 | 40340.9 | 1 | Homo sapiens (Human) | ||
| 3 | C (C) | Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 | polymer | 339 | 37285.7 | 1 | UniProt (P62873) Pfam (PF00400) | Homo sapiens (human) | Transducin beta chain 1 |
| 4 | D (D) | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 | polymer | 71 | 7861.1 | 1 | UniProt (P59768) Pfam (PF00631) | Homo sapiens (human) | G gamma-I |
| 5 | E (E) | ScFv16 protein | polymer | 251 | 26679.7 | 1 | Mus musculus (Mouse) | ||
| 6 | F (A) | methyl (3R)-4-[(3,4-dichlorophenyl)acetyl]-3-[(pyrrolidin-1-yl)methyl]piperazine-1-carboxylate | non-polymer | 414.3 | 1 | Chemie (U9I) |
Sequence modifications
A: 54 - 338 (UniProt: P41145)
| PDB | External Database | Details |
|---|---|---|
| Gly 52 | - | expression tag |
| Ser 53 | - | expression tag |
| Leu 135 | Ile 135 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 5 |
| Total formula weight | 144456.9 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 414.3 | |
| All* | Total formula weight | 144871.2 |
