8DZP

momSalB bound Kappa Opioid Receptor in complex with Gi1

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Kappa-type opioid receptor	polymer	308	34928.6	1	UniProt (P41145) Pfam (PF00001) In PDB	Homo sapiens (human)	K-OR-1,KOR-1
2	B	Guanine nucleotide-binding protein G(i) subunit alpha-1	polymer	354	40414.0	1	UniProt (P63096) Pfam (PF00503) In PDB	Homo sapiens (human)	Adenylate cyclase-inhibiting G alpha protein
3	C	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1	polymer	340	37342.8	1	UniProt (P62873) Pfam (PF00400) In PDB	Homo sapiens (human)	Transducin beta chain 1
4	D	Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2	polymer	71	7861.1	1	UniProt (P59768) Pfam (PF00631) In PDB	Homo sapiens (human)	G gamma-I
5	E	ScFv16 protein	polymer	251	26679.7	1		Mus musculus (Mouse)
6	A	methyl (2S,4aR,6aR,7R,9S,10aS,10bR)-2-(furan-3-yl)-9-(methoxymethoxy)-6a,10b-dimethyl-4,10-dioxododecahydro-2H-naphtho[2,1-c]pyran-7-carboxylate	non-polymer		434.5	1	Chemie (U99)

Sequence modifications

A: 54 - 358 (UniProt: P41145)

PDB	External Database	Details
Leu 51	-	expression tag
Gly 52	-	expression tag
Ser 53	-	expression tag
Leu 135	Ile 135	engineered mutation

B: 1 - 354 (UniProt: P63096)

PDB	External Database	Details
Asn 47	Ser 47	engineered mutation
Ala 203	Gly 203	engineered mutation
Ala 245	Glu 245	engineered mutation
Ser 326	Ala 326	engineered mutation

C: 2 - 340 (UniProt: P62873)

PDB	External Database	Details
Gly 1	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	5
	Total formula weight	147226.3
Non-Polymers*	Number of molecules	1
	Total formula weight	434.5
All*	Total formula weight	147660.7

*Water molecules are not included.