8DYV
Structure of human cytoplasmic dynein-1 bound to one Lis1
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Cytoplasmic dynein 1 heavy chain 1 | polymer | 3328 | 380953.6 | 1 | UniProt (Q14204) Pfam (PF08393) Pfam (PF18198) Pfam (PF18199) Pfam (PF12774) Pfam (PF17852) Pfam (PF12775) Pfam (PF22597) Pfam (PF12780) Pfam (PF12777) Pfam (PF12781) Pfam (PF03028) | Homo sapiens (human) | |
| 2 | B (B) | Platelet-activating factor acetylhydrolase IB subunit beta | polymer | 411 | 46722.9 | 1 | UniProt (P43034) Pfam (PF08513) Pfam (PF00400) | Homo sapiens (human) | Lissencephaly-1 protein,LIS-1,PAF acetylhydrolase 45 kDa subunit,PAF-AH 45 kDa subunit,PAF-AH alpha,PAFAH alpha |
| 3 | C, D, F (A) | ADENOSINE-5'-DIPHOSPHATE | non-polymer | 427.2 | 3 | Chemie (ADP) | |||
| 4 | E (A) | ADENOSINE-5'-TRIPHOSPHATE | non-polymer | 507.2 | 1 | Chemie (ATP) |
Sequence modifications
A: 1320 - 4646 (UniProt: Q14204)
B: 2 - 410 (UniProt: P43034)
| PDB | External Database | Details |
|---|---|---|
| Gly 1319 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Gly 0 | - | expression tag |
| Ser 1 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 427676.5 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 1788.8 | |
| All* | Total formula weight | 429465.3 |
