8DXO
Structure of LRRC8C-LRRC8A(IL125) Chimera, Class 2
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C, D, E... | Volume-regulated anion channel subunit LRRC8C,Volume-regulated anion channel subunit LRRC8A | polymer | 825 | 94747.7 | 7 | UniProt (Q8TDW0) UniProt (Q8IWT6) Pfam (PF12534) Pfam (PF13855) In PDB | Homo sapiens (human) | Factor for adipocyte differentiation 158,Leucine-rich repeat-containing protein 8C,Leucine-rich repeat-containing protein 8A,HsLRRC8A,Swelling protein 1 |
Sequence modifications
A, B, C, D, E, F, G: 1 - 176 (UniProt: Q8TDW0)
A, B, C, D, E, F, G: 176 - 177 (UniProt: Q8IWT6)
A, B, C, D, E, F, G: 177 - 802 (UniProt: Q8TDW0)
A, B, C, D, E, F, G: 176 - 177 (UniProt: Q8IWT6)
PDB | External Database | Details |
---|---|---|
Gly 177 | - | linker |
PDB | External Database | Details |
---|---|---|
- | Lys 717 | deletion |
Glu 803 | - | expression tag |
Asn 804 | - | expression tag |
Leu 805 | - | expression tag |
Tyr 806 | - | expression tag |
Phe 807 | - | expression tag |
Gln 808 | - | expression tag |
Gly 809 | - | expression tag |
Ala 810 | - | expression tag |
Ala 811 | - | expression tag |
Ala 812 | - | expression tag |
Gly 813 | - | expression tag |
Asp 814 | - | expression tag |
Tyr 815 | - | expression tag |
Lys 816 | - | expression tag |
Asp 817 | - | expression tag |
Asp 818 | - | expression tag |
Asp 819 | - | expression tag |
Asp 820 | - | expression tag |
Lys 821 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 7 |
Total formula weight | 663233.9 | |
All* | Total formula weight | 663233.9 |