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8DVY

DNA glycosylase MutY variant N146S in complex with DNA containing d(8-oxo-G) paired with an enzyme-generated abasic site product (AP) and crystalized with calcium acetate

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1AAdenine DNA glycosylasepolymer36541746.61UniProt (P83847)
Pfam (PF00730)
Pfam (PF00633)
Pfam (PF10576)
Pfam (PF14815)
In PDB
Geobacillus stearothermophilusoxoG:A-specific adenine glycosylase
2BDNA (5'-D(*AP*AP*GP*AP*CP*(8OG)P*TP*GP*GP*AP*C)-3')polymer113423.21synthetic construct
3CDNA (5'-D(*TP*GP*TP*CP*CP*AP*(AAB)P*GP*TP*CP*T)-3')polymer113207.11synthetic construct
4AIRON/SULFUR CLUSTERnon-polymer351.61Chemie (SF4)
5AACETATE IONnon-polymer59.01Chemie (ACT)
6A, CCALCIUM IONnon-polymer40.13Chemie (CA)
7waterwater18.024Chemie (HOH)
Sequence modifications
A: 1 - 365 (UniProt: P83847)
PDBExternal DatabaseDetails
Ser 146Asn 146engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains3
Total formula weight48376.9
Non-Polymers*Number of molecules5
Total formula weight530.9
All*Total formula weight48907.8
*Water molecules are not included.

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PDB entries from 2024-06-12

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