8DVP
Glycosylase MutY variant N146S in complex with DNA containing d(8-oxo-G) paired with substrate purine
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Adenine DNA glycosylase | polymer | 365 | 41746.6 | 1 | UniProt (P83847) Pfam (PF00730) Pfam (PF00633) Pfam (PF10576) Pfam (PF14815) | Geobacillus stearothermophilus | oxoG:A-specific adenine glycosylase |
| 2 | B (B) | DNA (5'-D(*AP*AP*GP*AP*CP*(8OG)P*TP*GP*GP*AP*C)-3') | polymer | 11 | 3423.2 | 1 | synthetic construct | ||
| 3 | C (C) | DNA (5'-D(*TP*GP*TP*CP*CP*AP*(PRN)P*GP*TP*CP*T)-3') | polymer | 11 | 3309.2 | 1 | synthetic construct | ||
| 4 | D (A) | IRON/SULFUR CLUSTER | non-polymer | 351.6 | 1 | Chemie (SF4) | |||
| 5 | E (A) | ACETATE ION | non-polymer | 59.0 | 1 | Chemie (ACT) | |||
| 6 | F, G, H (A, C) | CALCIUM ION | non-polymer | 40.1 | 3 | Chemie (CA) | |||
| 7 | I, J, K (A, B, C) | water | water | 18.0 | 180 | Chemie (HOH) |
Sequence modifications
A: 1 - 365 (UniProt: P83847)
| PDB | External Database | Details |
|---|---|---|
| Ser 146 | Asn 146 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 48479.0 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 530.9 | |
| All* | Total formula weight | 49009.9 |
