8DV4
Crystal structure of the BC8B TCR-CD1b-PI complex
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | T-cell surface glycoprotein CD1b | polymer | 300 | 33530.7 | 1 | UniProt (P29016) Pfam (PF16497) Pfam (PF07654) In PDB | Homo sapiens (human) | |
2 | B | Beta-2-microglobulin | polymer | 99 | 11748.2 | 1 | UniProt (P61769) Pfam (PF07654) In PDB | Homo sapiens (human) | |
3 | D | T-cell receptor alpha variable TRAV9-2 | polymer | 207 | 22726.1 | 1 | Homo sapiens (human) | ||
4 | E | T-cell receptor beta variable TRBV6-2 | polymer | 245 | 27598.9 | 1 | Homo sapiens (human) | ||
5 | C | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 1 | In PDB GlyTouCan (G15407YE) | |||
6 | F | alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 748.7 | 1 | In PDB GlyTouCan (G81315DD) | |||
7 | A, D, E | 1,2-ETHANEDIOL | non-polymer | 62.1 | 6 | Chemie (EDO) | |||
8 | A | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) | |||
9 | A | alpha-D-mannopyranose | non-polymer | 180.2 | 1 | Chemie (MAN) | |||
10 | A | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 1 | Chemie (NAG) | |||
11 | A | tetracosyl octadecanoate | non-polymer | 621.1 | 1 | Chemie (CUY) | |||
12 | A, E | CHLORIDE ION | non-polymer | 35.5 | 3 | Chemie (CL) | |||
13 | A, B | SODIUM ION | non-polymer | 23.0 | 3 | Chemie (NA) | |||
14 | D | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOINOSITOL | non-polymer | 836.1 | 1 | Chemie (PIE) | |||
15 | water | water | 18.0 | 247 | Chemie (HOH) |
Sequence modifications
A: 2 - 278 (UniProt: P29016)
PDB | External Database | Details |
---|---|---|
Gly 279 | - | expression tag |
Ser 280 | - | expression tag |
Gly 281 | - | expression tag |
Leu 282 | - | expression tag |
Asn 283 | - | expression tag |
Asp 284 | - | expression tag |
Ile 285 | - | expression tag |
Phe 286 | - | expression tag |
Glu 287 | - | expression tag |
Ala 288 | - | expression tag |
Gln 289 | - | expression tag |
Lys 290 | - | expression tag |
Ile 291 | - | expression tag |
Glu 292 | - | expression tag |
Trp 293 | - | expression tag |
His 294 | - | expression tag |
Glu 295 | - | expression tag |
His 296 | - | expression tag |
His 297 | - | expression tag |
His 298 | - | expression tag |
His 299 | - | expression tag |
His 300 | - | expression tag |
His 301 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 95603.8 | |
Branched | Number of molecules | 2 |
Total formula weight | 1335.2 | |
Non-Polymers* | Number of molecules | 18 |
Total formula weight | 2590.5 | |
All* | Total formula weight | 99529.5 |