8DV4
Crystal structure of the BC8B TCR-CD1b-PI complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | T-cell surface glycoprotein CD1b | polymer | 300 | 33530.7 | 1 | UniProt (P29016) Pfam (PF16497) Pfam (PF07654) | Homo sapiens (human) | |
| 2 | B (B) | Beta-2-microglobulin | polymer | 99 | 11748.2 | 1 | UniProt (P61769) Pfam (PF07654) | Homo sapiens (human) | |
| 3 | C (D) | T-cell receptor alpha variable TRAV9-2 | polymer | 207 | 22726.1 | 1 | Homo sapiens (human) | ||
| 4 | D (E) | T-cell receptor beta variable TRBV6-2 | polymer | 245 | 27598.9 | 1 | Homo sapiens (human) | ||
| 5 | E (C) | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 1 | In PDB GlyTouCan (G15407YE) | |||
| 6 | F (F) | alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 748.7 | 1 | In PDB GlyTouCan (G81315DD) | |||
| 7 | G, M, S, T, U... (A, D, E) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 6 | Chemie (EDO) | |||
| 8 | H, O (A) | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) | |||
| 9 | I (A) | alpha-D-mannopyranose | non-polymer | 180.2 | 1 | Chemie (MAN) | |||
| 10 | J (A) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 1 | Chemie (NAG) | |||
| 11 | K (A) | tetracosyl octadecanoate | non-polymer | 621.1 | 1 | Chemie (CUY) | |||
| 12 | L, W, X (A, E) | CHLORIDE ION | non-polymer | 35.5 | 3 | Chemie (CL) | |||
| 13 | N, P, Q (A, B) | SODIUM ION | non-polymer | 23.0 | 3 | Chemie (NA) | |||
| 14 | R (D) | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOINOSITOL | non-polymer | 836.1 | 1 | Chemie (PIE) | |||
| 15 | AA, BA, Y, Z (D, E, A, B) | water | water | 18.0 | 247 | Chemie (HOH) |
Sequence modifications
A: 2 - 278 (UniProt: P29016)
| PDB | External Database | Details |
|---|---|---|
| Gly 279 | - | expression tag |
| Ser 280 | - | expression tag |
| Gly 281 | - | expression tag |
| Leu 282 | - | expression tag |
| Asn 283 | - | expression tag |
| Asp 284 | - | expression tag |
| Ile 285 | - | expression tag |
| Phe 286 | - | expression tag |
| Glu 287 | - | expression tag |
| Ala 288 | - | expression tag |
| Gln 289 | - | expression tag |
| Lys 290 | - | expression tag |
| Ile 291 | - | expression tag |
| Glu 292 | - | expression tag |
| Trp 293 | - | expression tag |
| His 294 | - | expression tag |
| Glu 295 | - | expression tag |
| His 296 | - | expression tag |
| His 297 | - | expression tag |
| His 298 | - | expression tag |
| His 299 | - | expression tag |
| His 300 | - | expression tag |
| His 301 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 95603.8 | |
| Branched | Number of molecules | 2 |
| Total formula weight | 1335.2 | |
| Non-Polymers* | Number of molecules | 18 |
| Total formula weight | 2590.5 | |
| All* | Total formula weight | 99529.5 |
