8DT7
X-ray structure of human acetylcholinesterase in complex with oxime MMB4 (hAChE-MMB4)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Acetylcholinesterase | polymer | 550 | 60288.0 | 2 | UniProt (P22303) Pfam (PF00135) | Homo sapiens (human) | AChE |
| 2 | C, H (A, B) | 1,1'-methylenebis{4-[(E)-(hydroxyimino)methyl]pyridin-1-ium} | non-polymer | 258.3 | 2 | Chemie (3VI) | |||
| 3 | D, E (A) | NITRATE ION | non-polymer | 62.0 | 2 | Chemie (NO3) | |||
| 4 | F, G, I, J (A, B) | GLYCEROL | non-polymer | 92.1 | 4 | Chemie (GOL) | |||
| 5 | K, L (A, B) | water | water | 18.0 | 798 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 547 (UniProt: P22303)
| PDB | External Database | Details |
|---|---|---|
| Gly -2 | - | expression tag |
| Pro -1 | - | expression tag |
| Leu 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 120576.0 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 1008.9 | |
| All* | Total formula weight | 121584.9 |
