8DT2
X-ray structure of human acetylcholinesterase inhibited by paraoxon (POX-hAChE)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Acetylcholinesterase | polymer | 550 | 60288.0 | 2 | UniProt (P22303) Pfam (PF00135) | Homo sapiens (human) | AChE |
| 2 | C, G (A, B) | DIETHYL PHOSPHONATE | non-polymer | 138.1 | 2 | Chemie (DEP) | |||
| 3 | D, E, H, I (A, B) | GLYCEROL | non-polymer | 92.1 | 4 | Chemie (GOL) | |||
| 4 | F, J (A, B) | DIMETHYL SULFOXIDE | non-polymer | 78.1 | 2 | Chemie (DMS) | |||
| 5 | K, L (A, B) | water | water | 18.0 | 162 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 547 (UniProt: P22303)
| PDB | External Database | Details |
|---|---|---|
| Gly -2 | - | expression tag |
| Pro -1 | - | expression tag |
| Leu 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 120576.0 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 800.8 | |
| All* | Total formula weight | 121376.8 |
