8DSY
PPARg bound to inverse agonist H3B-343
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Peroxisome proliferator-activated receptor gamma | polymer | 273 | 31151.2 | 2 | UniProt (P37231) Pfam (PF00104) | Homo sapiens (human) | PPAR-gamma,Nuclear receptor subfamily 1 group C member 3 |
| 2 | C, D (A, B) | {5-[(5-{[(4-tert-butylphenyl)methyl]carbamoyl}-2,3-dimethyl-1H-indol-1-yl)methyl]-2-chlorophenoxy}acetic acid | non-polymer | 533.1 | 2 | Chemie (TJC) | |||
| 3 | E, F (A, B) | water | water | 18.0 | 31 | Chemie (HOH) |
Sequence modifications
A, B: 234 - 505 (UniProt: P37231)
| PDB | External Database | Details |
|---|---|---|
| Gly 233 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 62302.4 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 1066.1 | |
| All* | Total formula weight | 63368.5 |
