8DSH
Human NAMPT in complex with quercitrin and AMPcP
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Nicotinamide phosphoribosyltransferase | polymer | 499 | 56666.1 | 2 | UniProt (P43490) Pfam (PF18127) Pfam (PF04095) In PDB | Homo sapiens (human) | NAmPRTase,Nampt,Pre-B-cell colony-enhancing factor 1,Pre-B cell-enhancing factor,Visfatin |
2 | A, B | PHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER | non-polymer | 425.2 | 2 | Chemie (A12) | |||
3 | A, B | 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4-oxo-4H-chromen-3-yl 6-deoxy-alpha-L-mannopyranoside | non-polymer | 448.4 | 2 | Chemie (QCT) | |||
4 | water | water | 18.0 | 554 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 491 (UniProt: P43490)
PDB | External Database | Details |
---|---|---|
Leu 492 | - | expression tag |
Glu 493 | - | expression tag |
His 494 | - | expression tag |
His 495 | - | expression tag |
His 496 | - | expression tag |
His 497 | - | expression tag |
His 498 | - | expression tag |
His 499 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 113332.2 | |
Non-Polymers* | Number of molecules | 4 |
Total formula weight | 1747.2 | |
All* | Total formula weight | 115079.4 |