8DS5
X-ray structure of the MK5890 Fab - CD27 antibody-antigen complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | CD27 antigen | polymer | 164 | 18459.9 | 1 | UniProt (P26842) Pfam (PF00020) | Homo sapiens (human) | CD27L receptor,T-cell activation antigen CD27,T14,Tumor necrosis factor receptor superfamily member 7 |
| 2 | B (B) | MK-5890 Fab light chain | polymer | 213 | 23426.9 | 1 | Mus musculus (mouse) | ||
| 3 | C (C) | MK-5890 Fab heavy chain | polymer | 224 | 23929.7 | 1 | Mus musculus (mouse) | ||
| 4 | D, E, F, G, I... (A, B, C) | CADMIUM ION | non-polymer | 112.4 | 6 | Chemie (CD) | |||
| 5 | H (B) | NONAETHYLENE GLYCOL | non-polymer | 414.5 | 1 | Chemie (2PE) | |||
| 6 | K, L, M (A, B, C) | water | water | 18.0 | 275 | Chemie (HOH) |
Sequence modifications
A: 21 - 177 (UniProt: P26842)
| PDB | External Database | Details |
|---|---|---|
| His 178 | - | expression tag |
| His 179 | - | expression tag |
| His 180 | - | expression tag |
| His 181 | - | expression tag |
| His 182 | - | expression tag |
| His 183 | - | expression tag |
| His 184 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 65816.6 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 1089.0 | |
| All* | Total formula weight | 66905.5 |
