8DRW
Product structure of SARS-CoV-2 Mpro C145A mutant in complex with nsp9-nsp10 (C9) cut site sequence
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... (A, B, C, D, E...) | Fusion protein of 3C-like proteinase nsp5 and nsp9-nsp10 (C9) cut site | polymer | 306 | 33843.6 | 14 | UniProt (P0DTD1) Pfam (PF05409) | Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2 2019-nCoV) | 3CL-PRO,3CLp,Main protease,Mpro,Non-structural protein 5,nsp5,SARS coronavirus main proteinase,nsp9 |
| 2 | AC, CB, HA, NC, O... (J, F, C, L, A...) | SODIUM ION | non-polymer | 23.0 | 12 | Chemie (NA) | |||
| 3 | CA, CD, DC, EB, EC... (B, N, J, F, C...) | PENTAETHYLENE GLYCOL | non-polymer | 238.3 | 22 | Chemie (1PE) | |||
| 4 | AA, AD, BA, BC, BD... (B, N, J, F, C...) | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 33 | Chemie (PEG) | |||
| 5 | AB, BB, EA, FA, GA... (E, B, F, J, C...) | PHOSPHATE ION | non-polymer | 95.0 | 27 | Chemie (PO4) | |||
| 6 | ED, FD, GD, HD, ID... (A, B, C, D, E...) | water | water | 18.0 | 210 | Chemie (HOH) |
Sequence modifications
A, B, C, D, E, F, G, H, I, J, K, L, M, N: 1 - 300 (UniProt: P0DTD1)
A, B, C, D, E, F, G, H, I, J, K, L, M, N: 301 - 306 (UniProt: P0DTD1)
| PDB | External Database | Details |
|---|---|---|
| Ala 145 | Cys 3408 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 14 |
| Total formula weight | 473810.5 | |
| Non-Polymers* | Number of molecules | 94 |
| Total formula weight | 11584.2 | |
| All* | Total formula weight | 485394.7 |
