8DRV
Product structure of SARS-CoV-2 Mpro C145A mutant in complex with nsp8-nsp9 (C8) cut site sequence
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C, D | Fusion protein of 3C-like proteinase nsp5 and nsp8-nsp9 (C8) cut site | polymer | 306 | 33801.6 | 4 | UniProt (P0DTD1) Pfam (PF05409) In PDB | Severe acute respiratory syndrome coronavirus 2 (2019-nCoV SARS-CoV-2) | 3CL-PRO,3CLp,Main protease,Mpro,Non-structural protein 5,nsp5,SARS coronavirus main proteinase,nsp8 |
2 | B | PENTAETHYLENE GLYCOL | non-polymer | 238.3 | 1 | Chemie (1PE) | |||
3 | water | water | 18.0 | 247 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 1 - 300 (UniProt: P0DTD1)
A, B, C, D: 301 - 306 (UniProt: P0DTD1)
PDB | External Database | Details |
---|---|---|
Ala 145 | Cys 3408 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 135206.3 | |
Non-Polymers* | Number of molecules | 1 |
Total formula weight | 238.3 | |
All* | Total formula weight | 135444.6 |