8DRT
Product structure of SARS-CoV-2 Mpro C145A mutant in complex with nsp6-nsp7 (C6) cut site sequence (form 2)
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | B, A | 3C-like proteinase nsp5 | polymer | 306 | 33801.6 | 2 | UniProt (P0DTD1) Pfam (PF05409) In PDB | Severe acute respiratory syndrome coronavirus 2 | 3CL-PRO,3CLp,Main protease,Mpro,Non-structural protein 5,nsp5,SARS coronavirus main proteinase |
2 | water | water | 18.0 | 603 | Chemie (HOH) |
Sequence modifications
B, A: 1 - 300 (UniProt: P0DTD1)
PDB | External Database | Details |
---|---|---|
Ala 145 | Cys 3408 | engineered mutation |
Lys 301 | - | expression tag |
Val 302 | - | expression tag |
Ala 303 | - | expression tag |
Thr 304 | - | expression tag |
Val 305 | - | expression tag |
Gln 306 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 67603.1 | |
All* | Total formula weight | 67603.1 |