8DRS
Product structure of SARS-CoV-2 Mpro C145A mutant in complex with nsp6-nsp7 (C6) cut site sequence
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (A, B, C) | 3C-like proteinase nsp5 | polymer | 306 | 33801.6 | 3 | UniProt (P0DTD1) Pfam (PF05409) | Severe acute respiratory syndrome coronavirus 2 | 3CL-PRO,3CLp,Main protease,Mpro,Non-structural protein 5,nsp5,SARS coronavirus main proteinase |
| 2 | D, E, F (A, B, C) | water | water | 18.0 | 526 | Chemie (HOH) |
Sequence modifications
A, B, C: 1 - 300 (UniProt: P0DTD1)
| PDB | External Database | Details |
|---|---|---|
| Ala 145 | Cys 3408 | engineered mutation |
| Lys 301 | - | expression tag |
| Val 302 | - | expression tag |
| Ala 303 | - | expression tag |
| Thr 304 | - | expression tag |
| Val 305 | - | expression tag |
| Gln 306 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 101404.7 | |
| All* | Total formula weight | 101404.7 |
