8DR9
Crystal structure of human ALDH2 in complex with NAD+ and PEG MME 550
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Aldehyde dehydrogenase, mitochondrial | polymer | 501 | 54540.6 | 2 | UniProt (P05091) Pfam (PF00171) In PDB | Homo sapiens (human) | ALDH class 2,ALDH-E2,ALDHI |
| 2 | A, B | CITRIC ACID | non-polymer | 192.1 | 2 | Chemie (CIT) | |||
| 3 | A, B | NICOTINAMIDE-ADENINE-DINUCLEOTIDE | non-polymer | 663.4 | 2 | Chemie (NAD) | |||
| 4 | A, B | SODIUM ION | non-polymer | 23.0 | 2 | Chemie (NA) | |||
| 5 | A, B | PENTAETHYLENE GLYCOL | non-polymer | 238.3 | 9 | Chemie (1PE) | |||
| 6 | water | water | 18.0 | 941 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 500 (UniProt: P05091)
| PDB | External Database | Details |
|---|---|---|
| Gly 0 | - | expression tag |
| Ser 302 | Cys 319 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 109081.2 | |
| Non-Polymers* | Number of molecules | 15 |
| Total formula weight | 3901.6 | |
| All* | Total formula weight | 112982.8 |
