8DPO

Crystal structure of Neisseria gonorrhoeae carbonic anhydrase with Acetazolamide

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, C, E, G)	Carbonic anhydrase	polymer	243	27315.7	4	UniProt (Q50940) Pfam (PF00194)	Neisseria gonorrhoeae	Carbonate dehydratase
2	E, I, N, T (A, C, E, G)	5-ACETAMIDO-1,3,4-THIADIAZOLE-2-SULFONAMIDE	non-polymer		222.2	4	Chemie (AZM)
3	F, J, O, U (A, C, E, G)	ZINC ION	non-polymer		65.4	4	Chemie (ZN)
4	G, H, K, L, M... (A, C, E, G)	SULFATE ION	non-polymer		96.1	11	Chemie (SO4)
5	AA, X, Y, Z (G, A, C, E)	water	water		18.0	101	Chemie (HOH)

Sequence modifications

A, C, E, G: 1 - 226 (UniProt: Q50940)

PDB	External Database	Details
His -16	-	expression tag
His -15	-	expression tag
His -14	-	expression tag
His -13	-	expression tag
His -12	-	expression tag
His -11	-	expression tag
Asp -10	-	expression tag
Ser -9	-	expression tag
Gly -8	-	expression tag
Leu -7	-	expression tag
Val -6	-	expression tag
Pro -5	-	expression tag
Arg -4	-	expression tag
Gly -3	-	expression tag
Ser -2	-	expression tag
His -1	-	expression tag
Met 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	109262.9
Non-Polymers*	Number of molecules	19
	Total formula weight	2207.3
All*	Total formula weight	111470.2

*Water molecules are not included.