8DP5

Structure of the PEAK3/14-3-3 complex

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Protein PEAK3	polymer	491	52357.0	2	UniProt (Q6ZS72)	Homo sapiens (human)
2	C (C)	14-3-3 protein beta/alpha	polymer	246	28114.4	1	UniProt (P31946) Pfam (PF00244)	Homo sapiens (human)	Protein 1054,Protein kinase C inhibitor protein 1,KCIP-1
3	D (D)	14-3-3 protein epsilon	polymer	255	29208.9	1	UniProt (P62258) Pfam (PF00244)	Homo sapiens (human)	14-3-3E
4	E, F (E, P)	Protein PEAK3 fragment	polymer	491	52437.0	2	UniProt (Q6ZS72)	Homo sapiens (human)

Sequence modifications

A, B: 1 - 473 (UniProt: Q6ZS72)

PDB	External Database	Details
Leu 474	-	expression tag
Glu 475	-	expression tag
Gly 476	-	expression tag
Gly 477	-	expression tag
Gly 478	-	expression tag
Gly 479	-	expression tag
Ala 480	-	expression tag
Asp 481	-	expression tag
Tyr 482	-	expression tag
Lys 483	-	expression tag
Asp 484	-	expression tag
Asp 485	-	expression tag
Asp 486	-	expression tag
Asp 487	-	expression tag
Lys 488	-	expression tag
Gly 489	-	expression tag
Pro 490	-	expression tag
Val 491	-	expression tag

E, P: 1 - 473 (UniProt: Q6ZS72)

PDB	External Database	Details
Leu 474	-	expression tag
Glu 475	-	expression tag
Gly 476	-	expression tag
Gly 477	-	expression tag
Gly 478	-	expression tag
Gly 479	-	expression tag
Ala 480	-	expression tag
Asp 481	-	expression tag
Tyr 482	-	expression tag
Lys 483	-	expression tag
Asp 484	-	expression tag
Asp 485	-	expression tag
Asp 486	-	expression tag
Asp 487	-	expression tag
Lys 488	-	expression tag
Gly 489	-	expression tag
Pro 490	-	expression tag
Val 491	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	266911.4
All*	Total formula weight	266911.4

*Water molecules are not included.