8DOC
Crystal structure of RPE65 in complex with compound 16e and palmitate
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Retinoid isomerohydrolase | polymer | 533 | 60935.0 | 1 | UniProt (Q28175) Pfam (PF03055) | Bos taurus (cattle) | All-trans-retinyl-palmitate hydrolase,Retinal pigment epithelium-specific 65 kDa protein,Retinol isomerase |
| 2 | B (A) | FE (II) ION | non-polymer | 55.8 | 1 | Chemie (FE2) | |||
| 3 | C (A) | 3-CYCLOHEXYL-1-PROPYLSULFONIC ACID | non-polymer | 221.3 | 1 | Chemie (CXS) | |||
| 4 | D (A) | PALMITIC ACID | non-polymer | 256.4 | 1 | Chemie (PLM) | |||
| 5 | E (A) | (1R)-1-[3-(cyclohexylmethoxy)phenyl]-3-(methylamino)propan-1-ol | non-polymer | 277.4 | 1 | Chemie (SYL) | |||
| 6 | F (A) | water | water | 18.0 | 346 | Chemie (HOH) |
Sequence modifications
A: 2 - 533 (UniProt: Q28175)
| PDB | External Database | Details |
|---|---|---|
| Ace 1 | - | acetylation |
| Leu 341 | Ser 341 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 60935.0 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 811.0 | |
| All* | Total formula weight | 61746.0 |
