8DL3

Crystal structure of the human queuine salvage enzyme DUF2419, complexed with queuine

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Queuosine salvage protein	polymer	344	39361.8	2	UniProt (Q5T6V5) Pfam (PF10343) In PDB	Homo sapiens (human)
2	A, B	2-amino-5-({[(1S,4S,5R)-4,5-dihydroxycyclopent-2-en-1-yl]amino}methyl)-3,7-dihydro-4H-pyrrolo[2,3-d]pyrimidin-4-one	non-polymer		277.3	2	Chemie (QEI)
3		water	water		18.0	194	Chemie (HOH)

Sequence modifications

A, B: 1 - 341 (UniProt: Q5T6V5)

PDB	External Database	Details
Gly -2	-	expression tag
Ser -1	-	expression tag
His 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	78723.6
Non-Polymers*	Number of molecules	2
	Total formula weight	554.6
All*	Total formula weight	79278.1

*Water molecules are not included.