Loading
PDBj
MenuPDBj@FacebookPDBj@X(formerly Twitter)PDBj@BlueSkyPDBj@YouTubewwPDB FoundationwwPDBDonate
RCSB PDBPDBeBMRBAdv. SearchSearch help

8DHH

DHODH IN COMPLEX WITH LIGAND 29

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Dihydroorotate dehydrogenase (quinone), mitochondrialpolymer36939984.71UniProt (Q02127)
Pfam (PF01180)
Homo sapiens (human)DHOdehase,Dihydroorotate oxidase
2B
(A)
FLAVIN MONONUCLEOTIDEnon-polymer456.31Chemie (FMN)
3C
(A)
OROTIC ACIDnon-polymer156.11Chemie (ORO)
4D
(A)
(6M)-N-(3-chloro-2-methoxy-5-methylpyridin-4-yl)-6-[4-ethyl-3-(hydroxymethyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-5-fluoro-2-{[(2S)-1,1,1-trifluoropropan-2-yl]oxy}pyridine-3-carboxamidenon-polymer548.91Chemie (TMK)
5E, F, G
(A)
ACETATE IONnon-polymer59.03Chemie (ACT)
6H
(A)
GLYCEROLnon-polymer92.11Chemie (GOL)
7I
(A)
SULFATE IONnon-polymer96.11Chemie (SO4)
8J
(A)
waterwater18.0284Chemie (HOH)
Sequence modifications
A: 30 - 396 (UniProt: Q02127)
PDBExternal DatabaseDetails
Gly 28-expression tag
Ala 29-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight39984.7
Non-Polymers*Number of molecules8
Total formula weight1526.6
All*Total formula weight41511.3
*Water molecules are not included.

237735

PDB entries from 2025-06-18

PDB statisticsPDBj update infoContact PDBjnumon