8DHH
DHODH IN COMPLEX WITH LIGAND 29
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Dihydroorotate dehydrogenase (quinone), mitochondrial | polymer | 369 | 39984.7 | 1 | UniProt (Q02127) Pfam (PF01180) In PDB | Homo sapiens (human) | DHOdehase,Dihydroorotate oxidase |
2 | A | FLAVIN MONONUCLEOTIDE | non-polymer | 456.3 | 1 | Chemie (FMN) | |||
3 | A | OROTIC ACID | non-polymer | 156.1 | 1 | Chemie (ORO) | |||
4 | A | (6M)-N-(3-chloro-2-methoxy-5-methylpyridin-4-yl)-6-[4-ethyl-3-(hydroxymethyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-5-fluoro-2-{[(2S)-1,1,1-trifluoropropan-2-yl]oxy}pyridine-3-carboxamide | non-polymer | 548.9 | 1 | Chemie (TMK) | |||
5 | A | ACETATE ION | non-polymer | 59.0 | 3 | Chemie (ACT) | |||
6 | A | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
7 | A | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
8 | water | water | 18.0 | 284 | Chemie (HOH) |
Sequence modifications
A: 30 - 396 (UniProt: Q02127)
PDB | External Database | Details |
---|---|---|
Gly 28 | - | expression tag |
Ala 29 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 39984.7 | |
Non-Polymers* | Number of molecules | 8 |
Total formula weight | 1526.6 | |
All* | Total formula weight | 41511.3 |