8DHG
DHODH IN COMPLEX WITH LIGAND 19
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Dihydroorotate dehydrogenase (quinone), mitochondrial | polymer | 369 | 39984.7 | 1 | UniProt (Q02127) Pfam (PF01180) In PDB | Homo sapiens (human) | DHOdehase,Dihydroorotate oxidase |
| 2 | A | FLAVIN MONONUCLEOTIDE | non-polymer | 456.3 | 1 | Chemie (FMN) | |||
| 3 | A | OROTIC ACID | non-polymer | 156.1 | 1 | Chemie (ORO) | |||
| 4 | A | (6M)-N-(2-chloro-4-methylpyridin-3-yl)-6-[4-ethyl-3-(hydroxymethyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-5-fluoro-2-{[(2S)-1,1,1-trifluoropropan-2-yl]oxy}pyridine-3-carboxamide | non-polymer | 518.8 | 1 | Chemie (T78) | |||
| 5 | A | SULFATE ION | non-polymer | 96.1 | 2 | Chemie (SO4) | |||
| 6 | A | ACETATE ION | non-polymer | 59.0 | 2 | Chemie (ACT) | |||
| 7 | A | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 8 | water | water | 18.0 | 339 | Chemie (HOH) |
Sequence modifications
A: 30 - 396 (UniProt: Q02127)
| PDB | External Database | Details |
|---|---|---|
| Gly 28 | - | expression tag |
| Ala 29 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 39984.7 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 1533.6 | |
| All* | Total formula weight | 41518.3 |
