8DGG

Structure of glycosylated LAG-3 homodimer

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Lymphocyte activation gene 3 protein	polymer	426	46209.7	2	UniProt (Q61790)	Mus musculus (house mouse)	LAG-3,Activation-induced cytidine deaminase-linked autoimmunity protein,Aida
2	C, E (C, E)	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		627.6	2	In PDB GlyTouCan (G47362BJ)
3	D (D)	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		424.4	1	In PDB GlyTouCan (G42666HT)
4	F (A)	alpha-L-fucopyranose	non-polymer		164.2	1	Chemie (FUC)
5	G, H, I, J (A, B)	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	4	Chemie (NAG)
6	K, L (A, B)	water	water		18.0	11	Chemie (HOH)

Sequence modifications

A, B: 23 - 442 (UniProt: Q61790)

PDB	External Database	Details
His 443	-	expression tag
His 444	-	expression tag
His 445	-	expression tag
His 446	-	expression tag
His 447	-	expression tag
His 448	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	92419.4
Branched	Number of molecules	3
	Total formula weight	1679.6
Non-Polymers*	Number of molecules	5
	Total formula weight	1049.0
All*	Total formula weight	95148.0

*Water molecules are not included.