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8DG8

Cryo-EM Structure of HPIV3 prefusion F trimer in complex with 3x1 Fab

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, D, E
(B, A, C)
Fusion glycoprotein F0polymer49554970.63Pfam (PF00523)
UniProt (by SIFTS) (P06828)
Human parainfluenza 3 virus (strain NIH 47885)
2B
(H)
3x1 monoclonal antibody, VH regionpolymer12813932.71Homo sapiens (human)
3C
(L)
3x1 monoclonal antibody, VL regionpolymer10811642.91Homo sapiens (human)
4F, G, H, I, J...
(B, A, C)
2-acetamido-2-deoxy-beta-D-glucopyranosenon-polymer221.29Chemie (NAG)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains5
Total formula weight190487.4
Non-Polymers*Number of molecules9
Total formula weight1990.9
All*Total formula weight192478.3
*Water molecules are not included.

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PDB entries from 2025-07-16

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