8DFH
Crystal structure of non-neutralizing / interfering human monoclonal antibody 42C3 Fab in complex with MSP1-19
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Merozoite surface protein 1 | polymer | 105 | 11759.9 | 1 | UniProt (Q8I0U8) Pfam (PF12946) In PDB | Plasmodium falciparum 3D7 | Merozoite surface antigens,PMMSA |
2 | H | 42C3 Fab Heavy Chain | polymer | 238 | 25443.5 | 1 | Homo sapiens (Human) | ||
3 | L | 42C3 Fab Light Chain | polymer | 216 | 23011.6 | 1 | Homo sapiens (Human) | ||
4 | water | water | 18.0 | 51 | Chemie (HOH) |
Sequence modifications
A: 1 - 93 (UniProt: Q8I0U8)
PDB | External Database | Details |
---|---|---|
Glu -2 | - | expression tag |
Thr -1 | - | expression tag |
Gly 0 | - | expression tag |
Ala 3 | Ser 1609 | engineered mutation |
Ala 48 | Thr 1654 | engineered mutation |
Gly 94 | - | expression tag |
Thr 95 | - | expression tag |
Lys 96 | - | expression tag |
His 97 | - | expression tag |
His 98 | - | expression tag |
His 99 | - | expression tag |
His 100 | - | expression tag |
His 101 | - | expression tag |
His 102 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 3 |
Total formula weight | 60215.0 | |
All* | Total formula weight | 60215.0 |