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8DFE

Crystal Structure of SARS-CoV-2 Main Protease (Mpro) S144L Mutant

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
3C-like proteinase nsp5polymer30633851.61UniProt (P0DTD1)
Pfam (PF05409)
Severe acute respiratory syndrome coronavirus 23CL-PRO,3CLp,Main protease,Mpro,Non-structural protein 5,nsp5,SARS coronavirus main proteinase
2B
(A)
waterwater18.0201Chemie (HOH)
Sequence modifications
A: 1 - 306 (UniProt: P0DTD1)
PDBExternal DatabaseDetails
Leu 144Ser 3407engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight33851.6
All*Total formula weight33851.6
*Water molecules are not included.

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PDB entries from 2025-06-11

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