8DF9
Structure of M. kandleri topoisomerase V in complex with DNA. 38 base pair asymmetric DNA complex
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Topoisomerase V | polymer | 854 | 97110.4 | 2 | UniProt (Q977W1) Pfam (PF13412) Pfam (PF21872) Pfam (PF21616) Pfam (PF14520) Pfam (PF22409) In PDB | Methanopyrus kandleri | Winged helix-turn-helix transcriptional regulator |
2 | S | DNA (33-MER) | polymer | 33 | 10203.6 | 1 | synthetic construct | ||
3 | T | DNA (33-MER) | polymer | 33 | 10096.5 | 1 | synthetic construct | ||
4 | U | DNA (5'-D(P*GP*CP*CP*TP*GP*CP*AP*CP*GP*AP*AP*GP*TP*AP*AP*GP*C)-3') | polymer | 17 | 5221.4 | 1 | synthetic construct | ||
5 | V, X | DNA (5'-D(P*TP*GP*CP*TP*TP*AP*CP*TP*TP*CP*GP*TP*GP*CP*AP*GP*GP*CP*CP*A)-3') | polymer | 20 | 6116.0 | 2 | synthetic construct | ||
6 | W | DNA (5'-D(P*GP*CP*CP*TP*GP*CP*AP*CP*GP*AP*AP*GP*TP*AP*AP*GP*CP*A)-3') | polymer | 18 | 5534.6 | 1 | synthetic construct | ||
7 | A, B | MAGNESIUM ION | non-polymer | 24.3 | 12 | Chemie (MG) | |||
8 | S, T | POTASSIUM ION | non-polymer | 39.1 | 2 | Chemie (K) | |||
9 | water | water | 18.0 | 30 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 854 (UniProt: Q977W1)
PDB | External Database | Details |
---|---|---|
Ala 809 | Lys 809 | engineered mutation |
Ala 820 | Lys 820 | engineered mutation |
Ala 831 | Lys 831 | engineered mutation |
Ala 835 | Lys 835 | engineered mutation |
Ala 846 | Lys 846 | engineered mutation |
Ala 851 | Lys 851 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 8 |
Total formula weight | 237508.9 | |
Non-Polymers* | Number of molecules | 14 |
Total formula weight | 369.9 | |
All* | Total formula weight | 237878.7 |