8DE9
Cryo-EM structure of the zebrafish two pore domain K+ channel TREK1 (K2P2.1) in DDM/POPE mixed micelles
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Potassium channel, subfamily K, member 2a | polymer | 321 | 35559.4 | 2 | UniProt (X1WC65) Pfam (PF07885) UniProt (by SIFTS) (F1QAI2) | Danio rerio (zebrafish) | |
| 2 | C (A) | (1S)-2-{[(2-AMINOETHOXY)(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL STEARATE | non-polymer | 720.0 | 1 | Chemie (PEV) | |||
| 3 | D, E, F (A) | POTASSIUM ION | non-polymer | 39.1 | 3 | Chemie (K) |
Sequence modifications
A, B: 1 - 321 (UniProt: X1WC65)
| PDB | External Database | Details |
|---|---|---|
| Gln 95 | Asn 95 | engineered mutation |
| Gln 122 | Asn 122 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 71118.8 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 837.3 | |
| All* | Total formula weight | 71956.1 |
