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8DE4

Native serotonin transporter in complex with 15B8 Fab in the presence of methamphetamine

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Transporterpolymer53960778.91UniProt (A0A4X1TV69)
Pfam (PF00209)
UniProt (by SIFTS) (F1RN70)
Sus scrofa (pig)
2B
(B)
15B8 Fab heavy chain variable domainpolymer11812980.51Mus musculus
3C
(C)
15B8 Fab light chain variable domainpolymer11011776.11Mus musculus
4D
(D)
2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranosebranched424.41In PDB
GlyTouCan (G42666HT)
5E
(A)
CHLORIDE IONnon-polymer35.51Chemie (CL)
6F, G
(A)
SODIUM IONnon-polymer23.02Chemie (NA)
7H
(A)
(2S)-N-methyl-1-phenylpropan-2-aminenon-polymer149.21Chemie (B40)
8I, J
(A)
CHOLESTEROL HEMISUCCINATEnon-polymer486.72Chemie (Y01)
9K
(A)
DODECYL-BETA-D-MALTOSIDEnon-polymer510.61Chemie (LMT)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains3
Total formula weight85535.5
BranchedNumber of molecules1
Total formula weight424.4
Non-Polymers*Number of molecules7
Total formula weight1714.7
All*Total formula weight87674.6
*Water molecules are not included.

246704

PDB entries from 2025-12-24

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