8DDW
cryo-EM structure of TRPM3 ion channel in complex with Gbg, tethered by ALFA-nanobody
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D | Transient receptor potential cation channel, subfamily M, member 3 | polymer | 1371 | 157812.9 | 4 | UniProt (Q5F4S7) Pfam (PF18139) Pfam (PF00520) Pfam (PF16519) In PDB | Mus musculus (house mouse) | |
| 2 | E, F, G, H | Unidentified segment at the N-terminus of TRPM3 | polymer | 17 | 1464.8 | 4 | Mus musculus | ||
| 3 | I | Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 | polymer | 339 | 37285.7 | 1 | UniProt (P62873) Pfam (PF00400) In PDB | Homo sapiens (human) | Transducin beta chain 1 |
| 4 | J | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 | polymer | 70 | 7713.9 | 1 | UniProt (P59768) Pfam (PF00631) In PDB | Homo sapiens (human) | G gamma-I |
Sequence modifications
J: 2 - 71 (UniProt: P59768)
| PDB | External Database | Details |
|---|---|---|
| Ser 68 | Cys 68 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 10 |
| Total formula weight | 682110.5 | |
| All* | Total formula weight | 682110.5 |
