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8DDC

Intramembrane recognition between transmembrane domains of IL-7R and common gamma chain

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Cytokine receptor common subunit gammapolymer343864.51UniProt (P34902)Mus musculus (house mouse)Interleukin-2 receptor subunit gamma,IL-2 receptor subunit gamma,IL-2R subunit gamma,IL-2RG,gammaC,p64
2B
(B)
Interleukin-7 receptor subunit alphapolymer313452.21UniProt (P16872)Mus musculus (house mouse)IL-7 receptor subunit alpha,IL-7R subunit alpha,IL-7R-alpha,IL-7RA
Sequence modifications
A: 253 - 286 (UniProt: P34902)
PDBExternal DatabaseDetails
Val 271Met 271engineered mutation
Phe 282Cys 282engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight7316.7
All*Total formula weight7316.7
*Water molecules are not included.

237735

PDB entries from 2025-06-18

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