8DBN
Human PRPS1-E307A engineered mutation with Phosphate, ATP, and R5P; Hexamer
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... (A, B, C, D, E...) | Ribose-phosphate pyrophosphokinase 1 | polymer | 318 | 34777.1 | 6 | UniProt (P60891) Pfam (PF13793) Pfam (PF14572) | Homo sapiens (human) | PPRibP,Phosphoribosyl pyrophosphate synthase I,PRS-I |
| 2 | AA, G, K, O, S... (F, A, B, C, D...) | ADENOSINE-5'-TRIPHOSPHATE | non-polymer | 507.2 | 6 | Chemie (ATP) | |||
| 3 | BA, H, L, P, T... (F, A, B, C, D...) | 5-O-phosphono-alpha-D-ribofuranose | non-polymer | 230.1 | 6 | Chemie (HSX) | |||
| 4 | CA, DA, I, J, M... (F, A, B, C, D...) | MAGNESIUM ION | non-polymer | 24.3 | 12 | Chemie (MG) |
Sequence modifications
A, B, C, D, E, F: 2 - 318 (UniProt: P60891)
| PDB | External Database | Details |
|---|---|---|
| Ser 1 | - | expression tag |
| Ala 307 | Glu 307 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 208662.5 | |
| Non-Polymers* | Number of molecules | 24 |
| Total formula weight | 4715.4 | |
| All* | Total formula weight | 213377.9 |
