8DBK
Human PRPS1 with Phosphate, ATP, and R5P; Hexamer with resolved catalytic loops
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... (A, B, C, D, E...) | Ribose-phosphate pyrophosphokinase 1 | polymer | 318 | 34835.1 | 6 | UniProt (P60891) Pfam (PF13793) Pfam (PF14572) | Homo sapiens (human) | PPRibP,Phosphoribosyl pyrophosphate synthase I,PRS-I |
| 2 | AA, FA, G, Q, V (E, F, A, C, D) | ADENOSINE-5'-TRIPHOSPHATE | non-polymer | 507.2 | 5 | Chemie (ATP) | |||
| 3 | BA, GA, H, R, W (E, F, A, C, D) | 5-O-phosphono-alpha-D-ribofuranose | non-polymer | 230.1 | 5 | Chemie (HSX) | |||
| 4 | CA, HA, I, N, S... (E, F, A, B, C...) | PHOSPHATE ION | non-polymer | 95.0 | 6 | Chemie (PO4) | |||
| 5 | DA, EA, IA, J, JA... (E, F, A, B, C...) | MAGNESIUM ION | non-polymer | 24.3 | 12 | Chemie (MG) | |||
| 6 | L (B) | 1-O-pyrophosphono-5-O-phosphono-alpha-D-ribofuranose | non-polymer | 390.1 | 1 | Chemie (PRP) | |||
| 7 | M (B) | ADENOSINE MONOPHOSPHATE | non-polymer | 347.2 | 1 | Chemie (AMP) | |||
| 8 | KA, LA, MA, NA, OA... (A, B, C, D, E...) | water | water | 18.0 | 12 | Chemie (HOH) |
Sequence modifications
A, B, C, D, E, F: 2 - 318 (UniProt: P60891)
| PDB | External Database | Details |
|---|---|---|
| Ser 1 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 209010.7 | |
| Non-Polymers* | Number of molecules | 30 |
| Total formula weight | 5285.2 | |
| All* | Total formula weight | 214296.0 |
