8DBK
Human PRPS1 with Phosphate, ATP, and R5P; Hexamer with resolved catalytic loops
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... (A, B, C, D, E...) | Ribose-phosphate pyrophosphokinase 1 | polymer | 318 | 34835.1 | 6 | UniProt (P60891) Pfam (PF13793) Pfam (PF14572) | Homo sapiens (human) | PPRibP,Phosphoribosyl pyrophosphate synthase I,PRS-I |
| 2 | AA, FA, G, Q, V (E, F, A, C, D) | ADENOSINE-5'-TRIPHOSPHATE | non-polymer | 507.2 | 5 | Chemie (ATP) | |||
| 3 | BA, GA, H, R, W (E, F, A, C, D) | 5-O-phosphono-alpha-D-ribofuranose | non-polymer | 230.1 | 5 | Chemie (HSX) | |||
| 4 | CA, HA, I, N, S... (E, F, A, B, C...) | PHOSPHATE ION | non-polymer | 95.0 | 6 | Chemie (PO4) PubChem (1061) | |||
| 5 | DA, EA, IA, J, JA... (E, F, A, B, C...) | MAGNESIUM ION | non-polymer | 24.3 | 12 | Chemie (MG) PubChem (888) | |||
| 6 | L (B) | 1-O-pyrophosphono-5-O-phosphono-alpha-D-ribofuranose | non-polymer | 390.1 | 1 | Chemie (PRP) PubChem (1041) PubChem (7339) PubChem (23616411) PubChem (24771812) PubChem (90395114) PubChem (92962115) PubChem (126970134) | |||
| 7 | M (B) | ADENOSINE MONOPHOSPHATE | non-polymer | 347.2 | 1 | Chemie (AMP) PubChem (16397049) PubChem (16760266) PubChem (224) PubChem (34768) PubChem (83862) PubChem (40467049) PubChem (40469468) PubChem (446048) PubChem (44348067) PubChem (45358029) PubChem (40459109) PubChem (515384) PubChem (46874558) PubChem (638042) PubChem (46875232) PubChem (57358045) PubChem (57879893) PubChem (57879902) PubChem (5316444) PubChem (5742864) PubChem (177678969) PubChem (6083) PubChem (1549371) PubChem (12163610) PubChem (12358355) PubChem (92144436) PubChem (122197642) PubChem (12358354) PubChem (162290139) PubChem (162946266) PubChem (171699505) | |||
| 8 | KA, LA, MA, NA, OA... (A, B, C, D, E...) | water | water | 18.0 | 12 | Chemie (HOH) |
Sequence modifications
A, B, C, D, E, F: 2 - 318 (UniProt: P60891)
| PDB | External Database | Details |
|---|---|---|
| Ser 1 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 209010.7 | |
| Non-Polymers* | Number of molecules | 30 |
| Total formula weight | 5285.2 | |
| All* | Total formula weight | 214296.0 |
