8D9U
AP-1, Arf1, Nef lattice on MHC-I lipopeptide incorporated narrow membrane tubes, centered on beta-Arf1
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, BA, CA, J... (C, H, J, X, K...) | ADP-ribosylation factor 1 | polymer | 181 | 20800.9 | 12 | UniProt (P84077) Pfam (PF00025) | Homo sapiens (human) | |
| 2 | C, DA, G, HA, L... (N, L, n, d, o...) | Protein Nef | polymer | 213 | 24364.4 | 12 | UniProt (Q90VU7) Pfam (PF00469) | Human immunodeficiency virus 1 | 3'ORF,Negative factor,F-protein |
| 3 | D, EA, M, NA, V... (Y, x, y, z, 0...) | HLA class I histocompatibility antigen, A alpha chain | polymer | 44 | 4542.9 | 6 | UniProt (P04439) Pfam (PF06623) | Homo sapiens (human) | Human leukocyte antigen A,HLA-A |
| 4 | E, FA, N, OA, W... (B, A, D, E, F...) | AP-1 complex subunit beta-1 | polymer | 949 | 104736.5 | 6 | UniProt (Q10567) Pfam (PF01602) Pfam (PF02883) Pfam (PF09066) | Homo sapiens (human) | Adaptor protein complex AP-1 subunit beta-1,Adaptor-related protein complex 1 subunit beta-1,Beta-1-adaptin,Beta-adaptin 1,Clathrin assembly protein complex 1 beta large chain,Golgi adaptor HA1/AP1 adaptin beta subunit |
| 5 | F, GA, O, PA, X... (G, R, T, U, V...) | AP-1 complex subunit gamma-1 | polymer | 601 | 68194.1 | 6 | UniProt (P22892) Pfam (PF01602) | Mus musculus (house mouse) | Adaptor protein complex AP-1 subunit gamma-1,Adaptor-related protein complex 1 subunit gamma-1,Clathrin assembly protein complex 1 gamma-1 large chain,Gamma-adaptin,Gamma1-adaptin,Golgi adaptor HA1/AP1 adaptin subunit gamma-1 |
| 6 | AB, H, IA, Q, RA... (M, i, j, k, l...) | AP-1 complex subunit mu-1 | polymer | 423 | 48606.7 | 6 | UniProt (P35585) Pfam (PF01217) Pfam (PF00928) | Mus musculus (house mouse) | AP-mu chain family member mu1A,Adaptor protein complex AP-1 subunit mu-1,Adaptor-related protein complex 1 subunit mu-1,Clathrin assembly protein complex 1 mu-1 medium chain 1,Clathrin coat assembly protein AP47,Clathrin coat-associated protein AP47,Golgi adaptor HA1/AP1 adaptin mu-1 subunit,Mu-adaptin 1,Mu1A-adaptin |
| 7 | AA, BB, I, JA, R... (S, s, t, u, v...) | AP-1 complex subunit sigma-3 | polymer | 154 | 18305.3 | 6 | UniProt (Q96PC3) Pfam (PF01217) | Homo sapiens (human) | Adaptor protein complex AP-1 subunit sigma-1C,Adaptor-related protein complex 1 subunit sigma-1C,Clathrin assembly protein complex 1 sigma-1C small chain,Golgi adaptor HA1/AP1 adaptin sigma-1C subunit,Sigma 1C subunit of AP-1 clathrin,Sigma-adaptin 1C,Sigma1C-adaptin |
| 8 | CB, EB, GB, IB, KB... (C, H, J, X, K...) | GUANOSINE-5'-TRIPHOSPHATE | non-polymer | 523.2 | 12 | Chemie (GTP) | |||
| 9 | DB, FB, HB, JB, LB... (C, H, J, X, K...) | MAGNESIUM ION | non-polymer | 24.3 | 12 | Chemie (MG) |
Sequence modifications
C, H, J, X, K, Z, O, a, P, b, Q, c: 2 - 181 (UniProt: P84077)
N, L, n, d, o, e, p, f, q, g, r, h: 2 - 206 (UniProt: Q90VU7)
Y, x, y, z, 0, 1: 334 - 365 (UniProt: P04439)
B, A, D, E, F, I: 1 - 949 (UniProt: Q10567)
G, R, T, U, V, W: 1 - 595 (UniProt: P22892)
| PDB | External Database | Details |
|---|---|---|
| Myr 1 | - | modified residue |
| PDB | External Database | Details |
|---|---|---|
| Myr 1 | - | modified residue |
| Gly 207 | - | expression tag |
| His 208 | - | expression tag |
| His 209 | - | expression tag |
| His 210 | - | expression tag |
| His 211 | - | expression tag |
| His 212 | - | expression tag |
| His 213 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Gly 328 | - | expression tag |
| Ala 329 | - | expression tag |
| Met 330 | - | expression tag |
| Gly 331 | - | expression tag |
| Ser 332 | - | expression tag |
| Cys 333 | - | expression tag |
| Ser 345 | Thr 345 | engineered mutation |
| Gly 349 | Ser 349 | engineered mutation |
| Ser 355 | Gly 355 | engineered mutation |
| Ala 363 | Cys 363 | engineered mutation |
| His 366 | - | expression tag |
| His 367 | - | expression tag |
| His 368 | - | expression tag |
| His 369 | - | expression tag |
| His 370 | - | expression tag |
| His 371 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Arg 359 | Lys 359 | engineered mutation |
| Lys 476 | Glu 476 | engineered mutation |
| PDB | External Database | Details |
|---|---|---|
| Glu 596 | - | expression tag |
| Asn 597 | - | expression tag |
| Leu 598 | - | expression tag |
| Tyr 599 | - | expression tag |
| Phe 600 | - | expression tag |
| Gln 601 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 54 |
| Total formula weight | 2008296.3 | |
| Non-Polymers* | Number of molecules | 24 |
| Total formula weight | 6569.8 | |
| All* | Total formula weight | 2014866.1 |
