8D5C
anti-HIV-1 gp120-sCD4 complex antibody CG10 Fab in complex with B41-sCD4
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | X, Y, Z | Envelope glycoprotein gp41 | polymer | 153 | 17357.8 | 3 | UniProt (B3UEZ6) Pfam (PF00517) UniProt (by SIFTS) (B3UES2) In PDB | Human immunodeficiency virus 1 | |
2 | A, B, C | Envelope glycoprotein gp160 | polymer | 516 | 57702.5 | 3 | UniProt (B3UES2) Pfam (PF00516) In PDB | Human immunodeficiency virus | Env polyprotein |
3 | D, E, F | T-cell surface glycoprotein CD4 | polymer | 183 | 20288.1 | 3 | UniProt (P01730) Pfam (PF00047) Pfam (PF05790) In PDB | Homo sapiens (human) | T-cell surface antigen T4/Leu-3 |
4 | H, I, P | CG10 Fab heavy chain | polymer | 228 | 24583.4 | 3 | Mus musculus | ||
5 | L, J, Q | CG10 Fab light chain | polymer | 218 | 23733.2 | 3 | Mus musculus |
Sequence modifications
X, Y, Z: 512 - 664 (UniProt: B3UEZ6)
A, B, C: 31 - 505 (UniProt: B3UES2)
PDB | External Database | Details |
---|---|---|
Pro 559 | Ile 563 | engineered mutation |
Cys 605 | Thr 609 | engineered mutation |
PDB | External Database | Details |
---|---|---|
Met -4 | - | expression tag |
Asp -3 | - | expression tag |
Ala -2 | - | expression tag |
Met -1 | - | expression tag |
Lys 0 | - | expression tag |
Arg 1 | - | expression tag |
Gly 2 | - | expression tag |
Leu 3 | - | expression tag |
Cys 4 | - | expression tag |
Cys 5 | - | expression tag |
Val 6 | - | expression tag |
Leu 7 | - | expression tag |
Leu 8 | - | expression tag |
Leu 9 | - | expression tag |
Cys 10 | - | expression tag |
Gly 11 | - | expression tag |
Ala 12 | - | expression tag |
Val 13 | - | expression tag |
Phe 14 | - | expression tag |
Val 15 | - | expression tag |
Ser 16 | - | expression tag |
Pro 17 | - | expression tag |
Ser 18 | - | expression tag |
Gln 19 | - | expression tag |
Glu 20 | - | expression tag |
Ile 21 | - | expression tag |
His 22 | - | expression tag |
Ala 23 | - | expression tag |
Arg 24 | - | expression tag |
Phe 25 | - | expression tag |
Arg 26 | - | expression tag |
Arg 27 | - | expression tag |
Gly 28 | - | expression tag |
Ala 29 | - | expression tag |
Arg 30 | - | expression tag |
Cys 501 | Ala 505 | conflict |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 15 |
Total formula weight | 430994.7 | |
All* | Total formula weight | 430994.7 |